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Stimulation of protease-activated receptor-2 inhibits airway eosinophilia, hyperresponsiveness and bronchoconstriction in a murine model of allergic inflammation

1. An emerging body of evidence indicates that PGE(2) has a privileged anti-inflammatory role within the airways. Stimulants of protease-activated receptor-2 (PAR(2)) inhibit airway smooth muscle tone in vitro and in vivo predominantly via cyclooxygenase (COX)-dependent generation of prostaglandin E...

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Detalhes bibliográficos
Main Authors: De Campo, Benjamin A, Henry, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576095/
https://ncbi.nlm.nih.gov/pubmed/15700024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706150
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