Llwytho...

The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β

Activation of NF-κB by bacterial LPS promotes the upregulation of proinflammatory cytokines that contribute to the pathogenesis of Gram-negative septic shock. LPS activation of NF-κB is dependent upon the interaction of two death domain–containing (DD-containing) proteins, MyD88 and IL-1 receptor–as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bannerman, Douglas D., Tupper, Joan C., Kelly, James D., Winn, Robert K., Harlan, John M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC150862/
https://ncbi.nlm.nih.gov/pubmed/11828002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14774
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