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The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β
Activation of NF-κB by bacterial LPS promotes the upregulation of proinflammatory cytokines that contribute to the pathogenesis of Gram-negative septic shock. LPS activation of NF-κB is dependent upon the interaction of two death domain–containing (DD-containing) proteins, MyD88 and IL-1 receptor–as...
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Autori principali: | , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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American Society for Clinical Investigation
2002
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150862/ https://ncbi.nlm.nih.gov/pubmed/11828002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14774 |
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