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Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle

During the development of skeletal muscle, myoblasts withdraw from the cell cycle and differentiate into myotubes. The insulin-like growth factors IGF-I and IGF-II, through their cognate tyrosine kinase receptor (IGF-I receptor), are known to play a role in this process. After withdrawal of myoblast...

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Autors principals: Fernández, Ana M., Dupont, Joëlle, Farrar, Roger P., Lee, Sukho, Stannard, Bethel, Le Roith, Derek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150853/
https://ncbi.nlm.nih.gov/pubmed/11827994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13503
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