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Optimizing IGF-I for skeletal muscle therapeutics

It is virtually undisputed that IGF-I promotes cell growth and survival. However, the presence of several IGF-I isoforms, vast numbers of intracellular signaling components, and multiple receptors results in a complex and highly regulated system by which IGF-I actions are mediated. IGF-I has long be...

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Detalles Bibliográficos
Publicado en:Growth Horm IGF Res
Main Authors: Philippou, Anastassios, Barton, Elisabeth R.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665094/
https://ncbi.nlm.nih.gov/pubmed/25002025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2014.06.003
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