Sulindac Sulfide, but Not Sulindac Sulfone, Inhibits Colorectal Cancer Growth

Sulindac sulfide, a metabolite of the nonsteroidal antiinflammatory drug (NSAID) sulindac sulfoxide, is effective at reducing tumor burden in both familial adenomatous polyposis patients and in animals with colorectal cancer. Another sulindac sulfoxide metabolite, sulindac sulfone, has been reported...

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Bibliographic Details
Main Authors: Williams, Christopher S, Goldman, Angela P, Sheng, Hongmiao, Morrow, Jason D, DuBois, Raymond N
Format: Artigo
Language:Inglês
Published: Stockton Press 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508136/
https://ncbi.nlm.nih.gov/pubmed/10933052
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