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The Cox inhibitor, sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells

EP4 expression in human glioblastoma cells correlates with growth on soft agar. The cyclooxygenase (COX) inhibitor, sulindac sulfide, first altered specificity protein-1 (Sp-1) and, early growth response gene-1 (Egr1) expression, then increased the expression of nonsteroidal anti-inflammatory drug-a...

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Bibliografiske detaljer
Main Authors: Kambe, Atsushi, Yoshioka, Hiroki, Kamitani, Hideki, Watanabe, Takashi, Baek, Seung Joon, Eling, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789193/
https://ncbi.nlm.nih.gov/pubmed/19934343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0140
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