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COX inhibitors directly alter gene expression: role in cancer prevention?

Inflammation is an important contributor to the development and progression of human cancers. Inflammatory lipid metabolites, prostaglandins, formed from arachidonic acid by prostaglandin H synthases commonly called cyclooxygenases (COXs) bind to specific receptors that activate signaling pathways d...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Wang, Xingya, Baek, Seung Joon, Eling, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772904/
https://ncbi.nlm.nih.gov/pubmed/22020924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-011-9301-4
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