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Regulation of EP4 expression via the Sp-1 transcription factor: Inhibition of expression by anti-cancer agents
For glioblastomas, COX-2 expression is linked to poor survival. COX-2 effects are mediated by the receptors EP2 and EP4, whose regulation is poorly understood. The expression of EP4, and activation or inhibition of EP4 activity in human glioblastoma T98G cells, was found to correlate with growth on...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443856/ https://ncbi.nlm.nih.gov/pubmed/18346464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.01.032 |
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