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Inhibition of cell transformation by sulindac sulfide is confined to specific oncogenic pathways

Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce the risk of colorectal cancer (CRC). They are also known to induce the regression of colorectal adenomas, which are precursors to CRC. Despite these evidences, the exact mechanism by which NSAIDs exerts its anti-oncogenic effec...

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Autori principali: Gala, Manish, Sun, Ronggai, Yang, Vincent W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693486/
https://ncbi.nlm.nih.gov/pubmed/11734340
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