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Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors
BACKGROUND: Specificity protein (Sp) transcription factors play pivotal roles in maintaining the phenotypes of many cancers. We hypothesized that the antineoplastic effects of sulindac and its metabolites were due, in part, to targeting downregulation of Sp transcription factors. METHODS: The functi...
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| Publicado no: | BMC Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682223/ https://ncbi.nlm.nih.gov/pubmed/26673922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1956-8 |
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