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Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors
BACKGROUND: Specificity protein (Sp) transcription factors play pivotal roles in maintaining the phenotypes of many cancers. We hypothesized that the antineoplastic effects of sulindac and its metabolites were due, in part, to targeting downregulation of Sp transcription factors. METHODS: The functi...
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| Vydáno v: | BMC Cancer |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682223/ https://ncbi.nlm.nih.gov/pubmed/26673922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1956-8 |
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