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Transcription-Dependent Degradation of Topoisomerase I-DNA Covalent Complexes
Topoisomerase I (Top I)-DNA covalent complexes represent a unique type of DNA lesion whose repair and processing remain unclear. In this study, we show that Top I-DNA covalent complexes transiently arrest RNA transcription in normal nontransformed cells. Arrest of RNA transcription is coupled to act...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2003
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150741/ https://ncbi.nlm.nih.gov/pubmed/12640119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2341-2350.2003 |
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