Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

The serine/threonine kinases, Akt1/PKBα, Akt2/PKBβ, and Akt3/PKBγ, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer cells is still not well defined. In the current study, we used an Akt1 antise...

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Hlavní autoři: Liu, Xuesong, Shi, Yan, Han, Edward K-H, Chen, Zehan, Rosenberg, Saul H, Giranda, Vincent L, Luo, Yan, Ng, Shi-Chung
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2001
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505865/
https://ncbi.nlm.nih.gov/pubmed/11571628
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