Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

The serine/threonine kinases, Akt1/PKBα, Akt2/PKBβ, and Akt3/PKBγ, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer cells is still not well defined. In the current study, we used an Akt1 antise...

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Detalhes bibliográficos
Main Authors: Liu, Xuesong, Shi, Yan, Han, Edward K-H, Chen, Zehan, Rosenberg, Saul H, Giranda, Vincent L, Luo, Yan, Ng, Shi-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1505865/
https://ncbi.nlm.nih.gov/pubmed/11571628
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