Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

IL-13 potently stimulates eosinophilic and lymphocytic inflammation and alveolar remodeling in the lung, effects that depend on the induction of various matrix metalloproteinases (MMPs). Here, we compared the remodeling and inflammatory effects of an IL-13 transgene in lungs of wild-type, MMP-9–defi...

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Main Authors: Lanone, Sophie, Zheng, Tao, Zhu, Zhou, Liu, Wei, Lee, Chun Geun, Ma, Bing, Chen, Qingsheng, Homer, Robert J., Wang, Jingming, Rabach, Lesley A., Rabach, Morgan E., Shipley, J. Michael, Shapiro, Steven D., Senior, Robert M., Elias, Jack A.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC150413/
https://ncbi.nlm.nih.gov/pubmed/12189240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14136
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