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Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

IL-13 potently stimulates eosinophilic and lymphocytic inflammation and alveolar remodeling in the lung, effects that depend on the induction of various matrix metalloproteinases (MMPs). Here, we compared the remodeling and inflammatory effects of an IL-13 transgene in lungs of wild-type, MMP-9–defi...

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Uloženo v:
Vydáno v:J Clin Invest
Hlavní autoři: Lanone, Sophie, Zheng, Tao, Zhu, Zhou, Liu, Wei, Lee, Chun Geun, Ma, Bing, Chen, Qingsheng, Homer, Robert J., Wang, Jingming, Rabach, Lesley A., Rabach, Morgan E., Shipley, J. Michael, Shapiro, Steven D., Senior, Robert M., Elias, Jack A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12189240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14136
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