Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

IL-13 potently stimulates eosinophilic and lymphocytic inflammation and alveolar remodeling in the lung, effects that depend on the induction of various matrix metalloproteinases (MMPs). Here, we compared the remodeling and inflammatory effects of an IL-13 transgene in lungs of wild-type, MMP-9–defi...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Lanone, Sophie, Zheng, Tao, Zhu, Zhou, Liu, Wei, Lee, Chun Geun, Ma, Bing, Chen, Qingsheng, Homer, Robert J., Wang, Jingming, Rabach, Lesley A., Rabach, Morgan E., Shipley, J. Michael, Shapiro, Steven D., Senior, Robert M., Elias, Jack A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150413/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12189240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14136
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