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Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

IL-13 potently stimulates eosinophilic and lymphocytic inflammation and alveolar remodeling in the lung, effects that depend on the induction of various matrix metalloproteinases (MMPs). Here, we compared the remodeling and inflammatory effects of an IL-13 transgene in lungs of wild-type, MMP-9–defi...

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Опубликовано в::J Clin Invest
Главные авторы: Lanone, Sophie, Zheng, Tao, Zhu, Zhou, Liu, Wei, Lee, Chun Geun, Ma, Bing, Chen, Qingsheng, Homer, Robert J., Wang, Jingming, Rabach, Lesley A., Rabach, Morgan E., Shipley, J. Michael, Shapiro, Steven D., Senior, Robert M., Elias, Jack A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12189240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14136
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