Yüklüyor......
Nuclear export of the APC tumour suppressor controls β-catenin function in transcription
The adenomatous polyposis coli (APC) protein is inactivated in most colorectal tumours. APC loss is an early event in tumorigenesis, and causes an increase of nuclear β-catenin and its transcriptional activity. This is thought to be the driving force for tumour progression. APC shuttles in and out o...
Kaydedildi:
| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2003
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150338/ https://ncbi.nlm.nih.gov/pubmed/12606575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg105 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|