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ICP0 and the U(S)3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression
SK-N-SH cells exposed to low ratios of ICP0-null (ΔICP0) mutants of herpes simplex virus per cell express the viral α proteins, but the progression to β and γ gene expression does not ensue. In these restrictive cells, post-α gene expression can be induced after exposure of the infected cells to sod...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502567/ https://ncbi.nlm.nih.gov/pubmed/16785443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604142103 |
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