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The Two Functions of Herpes Simplex Virus 1 ICP0, Inhibition of Silencing by the CoREST/REST/HDAC Complex and Degradation of PML, Are Executed in Tandem
ICP0, an α (immediate-early) protein of herpes simplex virus 1, performs at least two key functions. It blocks inhibition of viral-gene expression by interferon, a function dependent on the degradation of the ND10 components PML and SP100 by the ubiquitin ligase expressed by the RING finger (RF), an...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
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American Society for Microbiology (ASM)
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612314/ https://ncbi.nlm.nih.gov/pubmed/18945770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01940-08 |
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