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ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells
The herpes simplex virus 1 ICP0 is a regulatory protein. Early in infection ICP0 localizes in ND10 bodies and performs two functions: As an E3 ligase in conjunction with E2 UbcH5a conjugating enzyme, it degrades the ND10 components PML and SP100. Concurrently, it suppresses the silencing of viral DN...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732861/ https://ncbi.nlm.nih.gov/pubmed/19706544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906905106 |
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