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During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins
ICP0 is a multifunctional herpes simplex virus protein known primarily as a promiscuous transactivator. In the course of productive infection, it is localized during the first 5–7 h in the nucleus and later in the cytoplasm. In the nucleus, its primary activities are to suppress the silencing of vir...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776466/ https://ncbi.nlm.nih.gov/pubmed/19850872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910920106 |
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