Loading...
DNA crosslinking and biological activity of a hairpin polyamide–chlorambucil conjugate
A prototype of a novel class of DNA alkylating agents, which combines the DNA crosslinking moiety chlorambucil (Chl) with a sequence-selective hairpin pyrrole–imidazole polyamide ImPy-β-ImPy-γ-ImPy-β-Dp (polyamide 1), was evaluated for its ability to damage DNA and induce biological responses. Polya...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150233/ https://ncbi.nlm.nih.gov/pubmed/12582240 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|