Llwytho...

DNA crosslinking and biological activity of a hairpin polyamide–chlorambucil conjugate

A prototype of a novel class of DNA alkylating agents, which combines the DNA crosslinking moiety chlorambucil (Chl) with a sequence-selective hairpin pyrrole–imidazole polyamide ImPy-β-ImPy-γ-ImPy-β-Dp (polyamide 1), was evaluated for its ability to damage DNA and induce biological responses. Polya...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yong-Dong, Dziegielewski, Jaroslaw, Wurtz, Nicholas R., Dziegielewska, Barbara, Dervan, Peter B., Beerman, Terry A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC150233/
https://ncbi.nlm.nih.gov/pubmed/12582240
Tagiau: Ychwanegu Tag
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