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DNA sequence selectivity of hairpin polyamide turn units

A class of hairpin polyamides linked by 3,4-diaminobutyric acid, resulting in a β-amine residue at the turn unit, showed improved binding affinities relative to their α-amino-γ-turn analogs for particular sequences. We incorporated β-amino-γ-turns in six-ring polyamides and determined whether there...

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書誌詳細
主要な著者: Farkas, Michelle E., Li, Benjamin C., Dose, Christian, Dervan, Peter B.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062503/
https://ncbi.nlm.nih.gov/pubmed/19349175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.03.072
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