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Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice
Retinoic acid (RA), the active derivative of vitamin A, is involved in various developmental and homeostatic processes. To define whether certain developmental events are particularly sensitive to a decrease in embryonic RA levels, we generated mice bearing a hypomorphic allele of the RA-synthesizin...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149907/ https://ncbi.nlm.nih.gov/pubmed/12563036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437920100 |
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