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Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice

Retinoic acid (RA), the active derivative of vitamin A, is involved in various developmental and homeostatic processes. To define whether certain developmental events are particularly sensitive to a decrease in embryonic RA levels, we generated mice bearing a hypomorphic allele of the RA-synthesizin...

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Bibliografiske detaljer
Main Authors: Vermot, Julien, Niederreither, Karen, Garnier, Jean-Marie, Chambon, Pierre, Dollé, Pascal
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149907/
https://ncbi.nlm.nih.gov/pubmed/12563036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437920100
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