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Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome
RATIONALE: Loss of Tbx1 and decrease of retinoic acid (RA) synthesis result in DiGeorge/Velo-Cardio-Facial syndrome (DGS/VCFS)-like phenotypes in mouse models, including defects in septation of the outflow tract (OFT) of the heart and anomalies of pharyngeal arch-derived structures including arterie...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864540/ https://ncbi.nlm.nih.gov/pubmed/20110535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.205732 |
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