Retinoic acid deficiency alters second heart field formation

Retinoic acid (RA), the active derivative of vitamin A, has been implicated in various steps of cardiovascular development. The retinaldehyde dehydrogenase 2 (RALDH2) enzyme catalyzes the second oxidative step in RA biosynthesis and its loss of function creates a severe embryonic RA deficiency. Rald...

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Autors principals: Ryckebusch, Lucile, Wang, Zengxin, Bertrand, Nicolas, Lin, Song-Chang, Chi, Xuan, Schwartz, Robert, Zaffran, Stéphane, Niederreither, Karen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268559/
https://ncbi.nlm.nih.gov/pubmed/18287057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712344105
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