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Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome

RATIONALE: Loss of Tbx1 and decrease of retinoic acid (RA) synthesis result in DiGeorge/Velo-Cardio-Facial syndrome (DGS/VCFS)-like phenotypes in mouse models, including defects in septation of the outflow tract (OFT) of the heart and anomalies of pharyngeal arch-derived structures including arterie...

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Autors principals: Ryckebüsch, Lucile, Bertrand, Nicolas, Mesbah, Karim, Bajolle, Fanny, Niederreither, Karen, Kelly, Robert G., Zaffran, Stéphane
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864540/
https://ncbi.nlm.nih.gov/pubmed/20110535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.205732
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