Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
β-Arrestins bind to activated G protein-coupled receptor kinase-phosphorylated receptors, which leads to their desensitization with respect to G proteins, internalization via clathrin-coated pits, and signaling via a growing list of “scaffolded” pathways. To facilitate the discovery of novel adaptor...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
2003
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12582207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262789099 |
| الوسوم: |
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