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Nef-Mediated Disruption of HLA-A2 Transport to the Cell Surface in T Cells

Human immunodeficiency virus type 1 (HIV-1) Nef is a key pathogenic factor necessary for the development of AIDS. One important function of Nef is to reduce cell surface levels of major histocompatibility complex class I (MHC-I) molecules, thereby protecting HIV-infected cells from recognition by cy...

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Bibliografiske detaljer
Main Authors: Kasper, Matthew R., Collins, Kathleen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149742/
https://ncbi.nlm.nih.gov/pubmed/12584329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3041-3049.2003
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