Human Immunodeficiency Virus Type 1 Nef Domains Required for Disruption of Major Histocompatibility Complex Class I Trafficking Are Also Necessary for Coprecipitation of Nef with HLA-A2

Human immunodeficiency virus type 1 (HIV-1) Nef is a critical protein that is necessary for HIV pathogenesis. Its roles include the disruption of major histocompatibility complex class I (MHC-I) and CD4 trafficking to promote immune evasion and viral spread. Mutational analyses have revealed that se...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Williams, Maya, Roeth, Jeremiah F., Kasper, Matthew R., Filzen, Tracey M., Collins, Kathleen L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2005
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596859/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.632-636.2005
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