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Human Immunodeficiency Virus Type 1 Nef Domains Required for Disruption of Major Histocompatibility Complex Class I Trafficking Are Also Necessary for Coprecipitation of Nef with HLA-A2

Human immunodeficiency virus type 1 (HIV-1) Nef is a critical protein that is necessary for HIV pathogenesis. Its roles include the disruption of major histocompatibility complex class I (MHC-I) and CD4 trafficking to promote immune evasion and viral spread. Mutational analyses have revealed that se...

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Udgivet i:J Virol
Principais autores: Williams, Maya, Roeth, Jeremiah F., Kasper, Matthew R., Filzen, Tracey M., Collins, Kathleen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.632-636.2005
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