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Human Immunodeficiency Virus Type 1 Nef Domains Required for Disruption of Major Histocompatibility Complex Class I Trafficking Are Also Necessary for Coprecipitation of Nef with HLA-A2

Human immunodeficiency virus type 1 (HIV-1) Nef is a critical protein that is necessary for HIV pathogenesis. Its roles include the disruption of major histocompatibility complex class I (MHC-I) and CD4 trafficking to promote immune evasion and viral spread. Mutational analyses have revealed that se...

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Détails bibliographiques
Auteurs principaux: Williams, Maya, Roeth, Jeremiah F., Kasper, Matthew R., Filzen, Tracey M., Collins, Kathleen L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC538737/
https://ncbi.nlm.nih.gov/pubmed/15596859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.632-636.2005
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