Topoisomerase Targeting with and Resistance to Gemifloxacin in Staphylococcus aureus
Gemifloxacin, a novel quinolone with potent activity against Staphylococcus aureus, was 8- to 16-fold more active against wild-type S. aureus than ciprofloxacin. The two- to fourfold increase in the MIC of gemifloxacin in genetically defined grlBA mutants and the twofold increase in a single gyrA mu...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499202/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.274-282.2003 |
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