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Topoisomerase Targeting with and Resistance to Gemifloxacin in Staphylococcus aureus
Gemifloxacin, a novel quinolone with potent activity against Staphylococcus aureus, was 8- to 16-fold more active against wild-type S. aureus than ciprofloxacin. The two- to fourfold increase in the MIC of gemifloxacin in genetically defined grlBA mutants and the twofold increase in a single gyrA mu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149033/ https://ncbi.nlm.nih.gov/pubmed/12499202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.274-282.2003 |
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