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Topoisomerase Targeting with and Resistance to Gemifloxacin in Staphylococcus aureus

Gemifloxacin, a novel quinolone with potent activity against Staphylococcus aureus, was 8- to 16-fold more active against wild-type S. aureus than ciprofloxacin. The two- to fourfold increase in the MIC of gemifloxacin in genetically defined grlBA mutants and the twofold increase in a single gyrA mu...

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Hlavní autoři: Ince, Dilek, Zhang, Xiamei, Silver, L. Christine, Hooper, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149033/
https://ncbi.nlm.nih.gov/pubmed/12499202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.1.274-282.2003
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