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Fitness Comparison of Thymidine Analog Resistance Pathways in Human Immunodeficiency Virus Type 1
Resistance to zidovudine (ZDV) results from thymidine analog resistance mutations (TAMs) at human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) codons 41, 67, 70, 210, 215, and 219. Two mutations are possible at codon 215: Y or F. Whereas T215Y occurs alone or with M41L and L210W...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489059/ https://ncbi.nlm.nih.gov/pubmed/16809307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02747-05 |
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