Actinomycin D Induces High-Level Resistance to Thymidine Analogs in Replication of Human Immunodeficiency Virus Type 1 by Interfering with Host Cell Thymidine Kinase Expression

Actinomycin D (ActD) is a transcription inhibitor and has been used in the treatment of certain forms of cancer. ActD has been reported to be a potential inhibitor of human immunodeficiency virus type 1 (HIV-1) replication due to its ability to inhibit reverse transcription. In contrast to what was...

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Detalhes bibliográficos
Main Authors: Imamichi, Tomozumi, Murphy, Michael A., Adelsberger, Joseph W., Yang, Jun, Watkins, Catherine M., Berg, Steve C., Baseler, Michael W., Lempicki, Richard A., Guo, Jianhui, Levin, Judith G., Lane, H. Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140776/
https://ncbi.nlm.nih.gov/pubmed/12502817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1011-1020.2003
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