High-Level Resistance to 3′-Azido-3′-Deoxythimidine due to a Deletion in the Reverse Transcriptase Gene of Human Immunodeficiency Virus Type 1

A variant of human immunodeficiency virus type 1 (HIV-1) possessing a deletion in the reverse transcriptase (RT) gene at codon 67 was identified in a patient who had failed combination antiretroviral therapy. This deletion initially emerged under the selective pressure of combination therapy with 3′...

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Detalles Bibliográficos
Main Authors: Imamichi, Tomozumi, Sinha, Tanima, Imamichi, Hiromi, Zhang, Yi-Ming, Metcalf, Julie A., Falloon, Judith, Lane, H. Clifford
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC111626/
https://ncbi.nlm.nih.gov/pubmed/10623768
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