High-Level Resistance to 3′-Azido-3′-Deoxythimidine due to a Deletion in the Reverse Transcriptase Gene of Human Immunodeficiency Virus Type 1

A variant of human immunodeficiency virus type 1 (HIV-1) possessing a deletion in the reverse transcriptase (RT) gene at codon 67 was identified in a patient who had failed combination antiretroviral therapy. This deletion initially emerged under the selective pressure of combination therapy with 3′...

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izdano v:	J Virol
Principais autores:	Imamichi, Tomozumi, Sinha, Tanima, Imamichi, Hiromi, Zhang, Yi-Ming, Metcalf, Julie A., Falloon, Judith, Lane, H. Clifford
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Vaccines and Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.1023-1028.2000
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