Relative Replication Fitness of a High-Level 3′-Azido-3′-Deoxythymidine-Resistant Variant of Human Immunodeficiency Virus Type 1 Possessing an Amino Acid Deletion at Codon 67 and a Novel Substitution (Thr→Gly) at Codon 69

The combination of an amino acid deletion at codon 67 (Δ67) and Thr-to-Gly change at codon 69 (T69G) in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is associated with high-level resistance to multiple RT inhibitors. To determine the relative contributions of the Δ67...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Imamichi, Tomozumi, Berg, Steve C., Imamichi, Hiromi, Lopez, Juan C., Metcalf, Julia A., Falloon, Judith, Lane, H. Clifford
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11069990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.23.10958-10964.2000
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