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Both Spike and Background Genes Contribute to Murine Coronavirus Neurovirulence

Various strains of mouse hepatitis virus (MHV) exhibit different pathogenic phenotypes. Infection with the A59 strain of MHV induces both encephalitis and hepatitis, while the highly neurovirulent JHM strain induces a fatal encephalitis with little, if any, hepatitis. The pathogenic phenotype for ea...

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Bibliografiske detaljer
Main Authors: Iacono, Kathryn T., Kazi, Lubna, Weiss, Susan R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489045/
https://ncbi.nlm.nih.gov/pubmed/16809289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00432-06
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