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Multiple regions of the murine coronavirus spike glycoprotein influence neurovirulence
The spike (S) glycoprotein of mouse hepatitis virus (MHV) is a major determinant of neurovirulence. Using targeted recombination we previously demonstrated that the S gene of the highly neurovirulent MHV-4 conferred a dramatic increase in neurovirulence to the mildly neurovirulent MHV-A59. To identi...
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| 發表在: | J Neurovirol |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer-Verlag
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7095106/ https://ncbi.nlm.nih.gov/pubmed/11582514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/135502801753170273 |
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