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Gene-Specific Contributions to Mumps Virus Neurovirulence and Neuroattenuation

Mumps virus (MuV) is highly neurotropic and was the leading cause of aseptic meningitis in the Western Hemisphere prior to widespread use of live attenuated MuV vaccines. Due to the absence of markers of virus neuroattenuation and neurovirulence, ensuring mumps vaccine safety has proven problematic,...

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Detalhes bibliográficos
Main Authors: Sauder, Christian J., Zhang, Cheryl X., Ngo, Laurie, Werner, Kellie, Lemon, Ken, Duprex, W. Paul, Malik, Tahir, Carbone, Kathryn, Rubin, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126569/
https://ncbi.nlm.nih.gov/pubmed/21543475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00245-11
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