Changes in Mumps Virus Gene Sequence Associated with Variability in Neurovirulent Phenotype

Mumps virus is highly neurotropic and, prior to widespread vaccination programs, was the major cause of viral meningitis in the United States. Nonetheless, the genetic basis of mumps virus neurotropism and neurovirulence was until recently not understood, largely due to the lack of an animal model....

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Bibliographische Detailangaben
Hauptverfasser: Rubin, Steven A., Amexis, Georgios, Pletnikov, Mikhail, Vanderzanden, Jacqueline, Mauldin, Jeremy, Sauder, Christian, Malik, Tahir, Chumakov, Konstantin, Carbone, Kathryn M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC229304/
https://ncbi.nlm.nih.gov/pubmed/14557647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11616-11624.2003
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