Changes in Mumps Virus Gene Sequence Associated with Variability in Neurovirulent Phenotype

Mumps virus is highly neurotropic and, prior to widespread vaccination programs, was the major cause of viral meningitis in the United States. Nonetheless, the genetic basis of mumps virus neurotropism and neurovirulence was until recently not understood, largely due to the lack of an animal model....

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Autors principals: Rubin, Steven A., Amexis, Georgios, Pletnikov, Mikhail, Vanderzanden, Jacqueline, Mauldin, Jeremy, Sauder, Christian, Malik, Tahir, Chumakov, Konstantin, Carbone, Kathryn M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC229304/
https://ncbi.nlm.nih.gov/pubmed/14557647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11616-11624.2003
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