Changes in Mumps Virus Gene Sequence Associated with Variability in Neurovirulent Phenotype

Mumps virus is highly neurotropic and, prior to widespread vaccination programs, was the major cause of viral meningitis in the United States. Nonetheless, the genetic basis of mumps virus neurotropism and neurovirulence was until recently not understood, largely due to the lack of an animal model....

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Hlavní autoři: Rubin, Steven A., Amexis, Georgios, Pletnikov, Mikhail, Vanderzanden, Jacqueline, Mauldin, Jeremy, Sauder, Christian, Malik, Tahir, Chumakov, Konstantin, Carbone, Kathryn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC229304/
https://ncbi.nlm.nih.gov/pubmed/14557647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11616-11624.2003
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