Evaluation of a Neonatal Rat Model for Prediction of Mumps Virus Neurovirulence in Humans

Neurovirulence of several mumps virus strains was assessed in a prototype rat neurovirulence test and compared to results obtained in the monkey neurovirulence test. The relative human neurovirulence of these strains was proportional to the severity of hydrocephalus in rats but not to lesion scores...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Rubin, Steven A., Pletnikov, Mikhail, Taffs, Rolf, Snoy, Phil J., Kobasa, Darwyn, Brown, Earl G., Wright, Kathryn E., Carbone, Kathryn M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.11.5382-5384.2000
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