Evaluation of a Neonatal Rat Model for Prediction of Mumps Virus Neurovirulence in Humans

Neurovirulence of several mumps virus strains was assessed in a prototype rat neurovirulence test and compared to results obtained in the monkey neurovirulence test. The relative human neurovirulence of these strains was proportional to the severity of hydrocephalus in rats but not to lesion scores...

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מידע ביבליוגרפי

הוצא לאור ב:	J Virol
Principais autores:	Rubin, Steven A., Pletnikov, Mikhail, Taffs, Rolf, Snoy, Phil J., Kobasa, Darwyn, Brown, Earl G., Wright, Kathryn E., Carbone, Kathryn M.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.11.5382-5384.2000
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